| District | Winner | Runner-Up | Other | Total Votes | |||||
|---|---|---|---|---|---|---|---|---|---|
| District 01 | Roger Wicker* (R) | 95,404 | 71.4% | Rex Weathers (D) | 32,318 | 24.2% | 5,845 [+] | 4.4% | 133,567 |
| District 02 | Bennie Thompson* (D) | 89,913 | 55.1% | Clinton LeSueur (R) | 69,711 | 42.8% | 3,426 [+] | 2.1% | 163,050 |
| District 03 | Chip Pickering* (R) | 139,329 | 63.6% | Ronnie Shows (D) | 76,184 | 34.8% | 3,638 [+] | 1.7% | 219,151 |
| District 04 | Gene Taylor* (D) | 121,742 | 75.2% | Karl Mertz (R) | 34,373 | 21.2% | 5,753 [+] | 3.6% | 161,868 |
| Total R vote: 338,817 (50.0%) Total D vote: 320,157 (47.2%) | |||||||||